MicroRNA‑29a contributes to intracranial aneurysm by regulating the mitochondrial apoptotic pathway
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چکیده
منابع مشابه
Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux.
We and others have recently shown that loss of the mitochondrial membrane potential (Deltapsi) precedes apoptosis and chemical-hypoxia-induced necrosis and is prevented by Bcl-2. In this report, we examine the biochemical mechanism used by Bcl-2 to prevent Deltapsi loss, as determined with mitochondria isolated from a cell line overexpressing human Bcl-2 or from livers of Bcl-2 transgenic mice....
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ژورنال
عنوان ژورنال: Molecular Medicine Reports
سال: 2018
ISSN: 1791-2997,1791-3004
DOI: 10.3892/mmr.2018.9257